Search results for " Bioreactor"

Harvesting Energy from Wastewater Using an Innovative Anaerobic Membrane Bioreactor

2015

Uncertainty assessment of a membrane bioreactor model using the GLUE methodology

2010

A mathematical model for the simulation of physical-biological organic removal by means of a membrane bioreactor (MBR) has been previously developed and tested. This paper presents an analysis of the uncertainty of the MBR model. Particularly, the research explores the applicability of the Generalised Likelihood Uncertainty Estimation (GLUE) methodology that is one of the most widely used methods for investigating the uncertainties in the hydrology and that now on is spreading in other research field. For the application of the GLUE methodology, several Monte Carlo simulations have been run varying the all model influential parameters simultaneously. The model was applied to an MBR pilot pl…

Membrane Fouling Mitigation in MBR via the Feast–Famine Strategy to Enhance PHA Production by Activated Sludge

2022

Fouling is considered one of the main drawbacks of membrane bioreactor (MBR) technology. Among the main fouling agents, extracellular polymeric substances (EPS) are considered one of the most impactful since they cause the decrease of sludge filterability and decline of membrane flux in the long term. The present study investigated a biological strategy to reduce the membrane-fouling tendency in MBR systems. This consisted of seeding the reactor with activated sludge enriched in microorganisms with polyhydroxyalkanoate (PHA) storage ability and by imposing proper operating conditions to drive the carbon toward intracellular (PHA) rather than extracellular (EPS) accumulation. For that purpos…

Analysis of Biomass Characteristics in MBR and MB-MBR Systems Fed with Synthetic Wastewater: Influence of a Gradual Salinity Increase

2014

The paper presents the results of a field gathering campaign carried out on two different pilot scale membrane bioreactor (MBR) systems, treating synthetic wastewater subject to a gradual increase of salinity. One was a conventional MBR system, while the other was a moving bed biofilm membrane bioreactor (MB-MBR), which combines suspended biomass and biofilm. Indeed, the presence of suspended carriers inside the bioreactor seems to give benefits due to the collisions between the circulating media and the membrane. The aim of the study was the comparison of two configurations in terms of biomass activity characterization and performance (pollutants removal and hydraulic behaviour). The resul…

Position paper - progress towards standards in integrated (aerobic) MBR modelling.

2020

Membrane bioreactor (MBR) models are useful tools for both design and management. The system complexity is high due to the involved number of processes which can be clustered in biological and physical ones. Literature studies are present and need to be harmonized in order to gain insights from the different studies and allow system optimization by applying a control. This position paper aims at defining the current state of the art of the main integrated MBR models reported in the literature. On the basis of a modelling review, a standardized terminology is proposed to facilitate the further development and comparison of integrated membrane fouling models for aerobic MBRs. ispartof: WATER …

The role of fouling mechanisms in a submerged membrane bioreactor during the start-up

2006

PLLA Scaffold with Gradient pore size in microphysiological tissue system bioreactor for Osteochondral regeneration

2015

Cartilage and bone tissues in the joints are intimately linked and form the osteochondral unit. A better understanding of both disease and regenerative processes of bone and cartilage requires the study of both tissues together, as part of the osteochondral unit to account for their mutual interactions. However, the production of scaffolds for osteochondral tissue regeneration is a challenging task, since scaffolds must mimic the differents morphologies of cartilage and bone. Thermally Induced Phase Separation (TIPS) is one of the most adaptable techniques to produce porous scaffold for Tissue Engineering applications. A wide range of morphologies in terms of both pore size and distribution…

Computational modeling and experimental characterization of fluid dynamics in micro-CT scanned scaffolds within a multiple-sample airlift perfusion b…

2023

The perfusion of flow during cell culture induces cell proliferation and enhances cellular activity. Perfusion bioreactors offer a controlled dynamic environment for reliable in vitro applications in the tissue engineering field. In this work, to evaluate the effects of the operating parameters of a custom-made bioreactor, numerical simulations were performed to solve the fluid velocity profile inside the bioreactor containing multi-grid support that allows allocating of multiple seeded scaffolds at the same time. The perfusion system exhibited a uniform distribution of liquid velocities within the regions, suitable for cell growth on seeded scaffolds. The effects of the porous microstructu…

In Vitro Regeneration of

2019

Three caper (Capparis spinosa L.) biotypes grown on the Sicilian island of Salina (38°33′49″ N) were micropropagated to evaluate two different in vitro culture systems: one using the traditional solid medium, and the other based on liquid culture in a PlantForm bioreactor. PlantForm is a temporary immersion system (TIS), a new propagation method in which the shoots undergo temporary immersion in a liquid medium in order to avoid the accumulation of gas through forced ventilation. This study proposes a protocol to improve the efficiency of in vitro propagation of caper plants, while also reducing production costs, because of the elimination of the gelling agent, and manual labor, requiring l…

Control of the Biodegradation of Mixed Wastes in a Continuous Bioreactor by a Type-2 Fuzzy Logic Controller

2009

Abstract Type-2 fuzzy logic control is proposed for nonlinear processes characterized by bifurcations. A control simulation study was conducted for a bioreactor with cell recycle containing phenol and glucose as carbon and energy sources in which a pure culture of Pseudomonas putida is carried out. The model developed by Ajbar [Ajbar, A. (2001). Stability analysis of the biodegradation of mixed wastes in a continuous bioreactor with cell recycle. Water Research, 35 (5), 1201–1208] was used for the simulations. The particular dynamics of the bioreactor, characterized by two saddle-node bifurcations, makes its control difficult, since it may become unstable also for small variations of some p…